"I hope that students will gain a more intuitive sense of cell and human physiology by applying fundamental principles from engineering to these subject areas. In other words, rather than purely memorizing facts, students should be able to apply their knowledge and make intelligent guesses when posed with new problems."
" I was a postdoctoral fellow at the Orthopaedic Research Laboratory from 1996- 1997 and was appointed as an Assistant Professor of Biomedical Engineering in June 1997. Hence, I have been a faculty member for about 1.5 years. My research involves cell and tissue engineering. With graduate and undergraduate students as well as collaborators from the Center for Biomedical Engineering in Fu SEAS and the Orthopaedic Research Laboratory (CPMC), my laboratory explores the mechanisms by which orthopaedic cells respond to various physical stimuli (e.g., shear stress, electric fields, growth factors). For example, an understanding of mechanotransduction, the process by which cells convert mechanical stimul (e.g., joint loading forces) into an intracellular signal (e.g., second messengers), may provide insights to how cells maintain the normal structure function of tissues and how they may participate in the etiology of pathology. Moreover, from knowledge of such basic mechanisms,strategies to optimize cellular signals for purposes of engineering replacement tissues (i.e., tissue engineering) can be developed."
1990 Sc.B. Bioengineering, Brown University; 1992 M.S.E. Bioengineering, Unviersity of Pennsylvania; 1995 Ph.D. Bioengineering, University of Pennsylvania
CUNIX ID: cth6